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PRINT: ISSN 2221-1896
ONLINE : ISSN 2223-0343
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Comparison of analgesia and cardio-pulmonary effects of epidural
injection of pethidine and lidocaine in small East African goats |
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Donald Gregory Mpanduji and Doreen Godfrey Ndossi
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Department of Veterinary Surgery and Theriogenology, Faculty of
Veterinary Medicine, Sokoine University of Agriculture, P.O. Box 3020,
Morogoro Tanzania
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Abstract |
Analgesic and cardiopulmonary effects of epidural injections of 2%
lidocaine (4mg/kg, n=6) and pethidine (2.5mg/kg, n=6) were compared in
healthy goats weighing 18-25 kg. All drugs were injected at lumbosacral
epidural space. Mean heart rate, respiration rate, rectal temperature,
analgesia effect (response to pinprick stimuli), sedation and motor
incoordination were determined. Results were recorded before and at
various times (every 5 minutes for the first 10 minutes and every 10
minutes upto 2 hrs) after the epidural injection. Onset of analgesia was
after 5 minutes following injection of either lidocaine or pethidine.
Duration of analgesia was over 120 minutes and 60 minutes after epidural
injection of lidocaine and pethidine respectively. Hind limb paralysis
was observed in goats that received lidocaine while only mild
incoordination was observed in pethidine treated goats except for one
goat that remained recumbent for the entire observation period.
Significant increase in body temperature was recorded in 10 minutes
after pethidine injection but did not change following lidocaine
injection. There was no significant change in heart rate following
epidural injection of lidocaine but significantly decreased following
pethidine injection. Respiration rate significantly increased in
lidocaine group but did not change in pethidine treated goats. Results
of this study indicate that epidural injection of pethidine at a dose of
2.5 mg/kg produce analgesia of a shorter duration compared to lidocaine,
but is sufficient and safe for short duration surgeries of the perineal
region in goats.
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Keywords:
Spinal analgesia; opiates; caprine; pain
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To cite this article:
Mpanduji, DG and Ndossi, DG, 2013. Comparison of
analgesia and cardio-pulmonary effects of epidural injection of
pethidine and lidocaine in Small East African goats. Res. Opin. Anim.
Vet. Sci., 3(2), 30-34. |
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