Rabbit production in Benin has been seriously affected by many outbreaks of Rabbit Haemorrhagic Disease between 1995 and 2015 which continue to be a major constraint for this activity. A cross sectional survey was done from October to November 2018 in Research and Development Sites of southern Benin to carry out the typology of rabbit farms considering biosecurity practices and vaccination against RHD and determine the influence of each type of rabbit farms on RHD occurrence. Forty rabbit farms were randomly sampled in height sites located respectively in municipalities of Kétou, Adjohoun, Sèmè-Podji, Tori-Bossito, Grand-Popo, Djakotomè, Zogbodomey and Sakété.  Blood samples were randomly collected by ear vein from one buck, two does and two growing rabbits from each of the sampled farms for antibodies against both RHDV and RHDV2 detection by competitive ELISA. Factor Analysis of Mixed Data and Hierarchical Clustering on Principal Components were performed for farm typology and quasipoisson model was run to check the influence of farm types on RHD occurrence. Surveyed rabbit farmers were mostly men (94.74%), are 45±13 years old in average, had secondary school (36.84%) or university (36.84%) level. They were very often monogamous (68.42%) and owned 111±118 rabbits in average. Three groups of similar farms had been identified: Group 1 and 3 characterized by disinfection of building and materials and use of footbaths with effective disinfectants, droppings collection, buildings cleaning and respectively not polygamous households and modern buildings; group 2 where farmers did not disinfect cages, buildings or feeders and waterers and did not use footbath, had polygamous household and did not have high education level. All the rabbits in surveyed farms were free from antibodies against the two variants RHDV1 and RHDV2 of RHD at the time of the study. Otherwise, RHD cases since 2015 were lower in farms in group 2 than in farms in groups 1 and 3. As biosecurity practices were better in groups 1 and 3 than in group 2, it may be inferred that the farms which have more previous cases of RHD observe more biosecurity measures.